|Statement||edited by Vincenzo Zappia ... [et al.].|
|Series||Advances in experimental medicine and biology -- v. 231.|
|Contributions||Zappia, Vincenzo., International Symposium on Post-Translational Modifications of Proteins and Aging (1st : 1987 : Naples, Italy)|
|LC Classifications||QP551 .A326 1988|
|The Physical Object|
|Pagination||xiii, 683 p. :|
|Number of Pages||683|
Note: Citations are based on reference standards. However, formatting rules can vary widely between applications and fields of interest or study. The specific requirements or preferences of your reviewing publisher, classroom teacher, institution or organization should be applied. Advances in Post-Translational Modifications of Proteins and Aging. () Post-Translational Modifications of the Insulin Receptor. In: Zappia V., Galletti P., Porta R., Wold F. (eds) Advances in Post-Translational Modifications of Proteins and Aging. Advances in Experimental Medicine and Biology, vol Buy this book on publisher's. Post-translational modification (PTM) refers to the covalent and generally enzymatic modification of proteins following protein happyplacekidsgym.comns are synthesized by ribosomes translating mRNA into polypeptide chains, which may then undergo PTM to form the mature protein product. PTMs are important components in cell signaling, as for example when prohormones are converted to hormones. A. Bürkle, in Encyclopedia of Genetics, Protein synthesis occurs during a process called ‘translation.’ Posttranslational modification of proteins refers to the chemical changes proteins may undergo after translation. Such modifications come in a wide variety of types, and are mostly catalyzed by enzymes that recognize specific target sequences in specific proteins.
Soderquist A.M., Todderud G., Carpenter G. () The Role of Carbohydrate as a Post-Translational Modification of the Receptor for Epidermal Growth Factor. In: Zappia V., Galletti P., Porta R., Wold F. (eds) Advances in Post-Translational Modifications of Proteins and Aging. Advances in Experimental Medicine and Biology, vol Springer Cited by: 8. Nov 20, · More than five percent of the genes in higher eukaryotic genomes encode enzymes that posttranslationally modify proteins, greatly expanding the complexity and diversity of proteomes. This book examines the molecular logic of the major types of covalent modifications of proteins and their biological happyplacekidsgym.com by: POST-TRANSLATIONAL MODIFICATION OF PROTEINS Although the amino acid sequence of a given protein is encoded in the nucleic acid sequence of its messenger RNA following transcription and process- ing, the ultimate biological function as well as the survival of a protein will depend on a number of different modifications which occur following Cited by: 1. Dec 10, · Post-translational modification (PTM) is one of the mechanisms by which protein function is regulated by chronic hypoxia. This article presents an overview of recent findings on PTM of proteins induced by chronic intermittent hypoxia (CIH) which is experienced by humans with sleep disordered breathing resulting in autonomic abnormalities.
Protein Posttranslational Modifications in Aging. Permalink Read 1 Comment Add a Comment Posted by Reason. This very readable review paper walks through what is known of modifications to proteins that occur after their creation, and the role these modifications play in aging. Post-translational modifications (PTM) in histone,1,2 DNA methylation3,4 mechanisms, and gene therapy are emerging fields; hence details of their processes need to be rigorously explored. Invariably, chromatin remodeling, which is an epigenetic modification, requires a great deal of ATP to form complexes which tend to shift and alter the. Proteins are also covalently linked to tags that target a protein for degradation. Besides single modifications, proteins are often modified through a combination of post-translational cleavage and the addition of functional groups through a step-wise mechanism of protein maturation or activation. Jun 15, · Post-translational modifications (PTMs) are critical to the function of many proteins in living systems, and understanding their effects at the molecular level is important for both basic and applied research in biology and medicine. To further this understanding, open databases of curated PTM information have been happyplacekidsgym.com by: 4.